Miniature Fluidic Devices for Rapid Biological Detection by Sang-Hyun Oh Carlos Escobedo & Alexandre G. Brolo

Author:Sang-Hyun Oh, Carlos Escobedo & Alexandre G. Brolo
Language: eng
Format: epub
Publisher: Springer International Publishing, Cham

These results reveal the potential of an evaporation -based delivery scheme on nanoplasmonic sensors. This method increases device performance by performing analyte concentration and lowering the limit of detection. Biological particles can be trapped at nanostructured sites, without the need for any chemical modification of the surface, enabling their on-chip analysis. The platform itself is very simple to use as it does not require any assemblies, external power sources or training. Simply addition of a droplet on to the chip is sufficient to enable concentration of molecules. The limitations of this method include reliance on rate of evaporation which can be dependent on many factors such as area of the liquid–air interface and ambient conditions.

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